sepantronium bromide (PC-002) - Cothera Biosci
Pain-Related PANoptosis Gene Signature Predicts Prognosis and Guides Therapy in Oral Squamous Cell Carcinoma. (PubMed, Technol Cancer Res Treat) - Jul 21, 2026 - "GSEA identified activated pathways like autophagy and chemokine signaling in high-risk patients.ConclusionsThe pain-related PANoptosis-gene model effectively stratifies OSCC patients by risk. Sepantronium bromide may represent a potential therapeutic candidate for high-risk patients; however, further experimental validation is required." 
Biomarker • Gene Signature • Journal • Oncology • Oral Cancer • Pain • Squamous Cell Carcinoma • CA9 • IGLL5
http://www.ncbi.nlm.nih.gov/pubmed/42474130
 
Qi Liu; Silu Chen; Xiang Gao; Yan Wang; Ying Yao
 
Jul 21, 2026
 
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