Proteomic Cysteine Profiling Links DMI and DMF to Antiviral Activity. (PubMed, Proteomics) - Sep 26, 2026 - "Our findings nominate RIG-I as a shared candidate target of DMI and DMF and associate altered cysteine reactivity with the dampening of antiviral and inflammatory signaling. This work provides new mechanistic insights into the immunosuppressive actions of these electrophiles and highlights their potential as chemical probes and therapeutic leads for modulating innate immunity."
Journal • DDX58
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Giulio Srubek Tomassy; Jea-Hyun Baek; Kyong-Tai Kim; Lu Zhang; Sung Wook Kim; Woo-Seok Byun
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