Obinutuzumab Facilitates Tubular Repair in Lupus Nephritis Independently of Histologic or Clinical Response: Post Hoc Analyses of Urine Epidermal Growth Factor in the Phase 3 REGENCY Trial (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #SA-PO0806; Pres time: Oct 24, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; P3 | "Conclusion uEGF levels were associated with kidney histology changes during treatment and increased uEGF levels were observed alongside the resolution of clinical and histologic activity. uEGF also improved with OBI even in non-responders, suggesting OBI may improve tubular health independent of complete clinical or histologic resolution."
Clinical • P3 data • Retrospective data • Chronic Kidney Disease • Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Renal Disease • EGF
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Holly Clarke; Juan M. Mejia-Vilet; Ben Lanza; Peiqing Yu; Theodore A. Omachi; William Franklin Pendergraft; Harini Raghu; Brad Rovin
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