Anti-Contactin-1-Associated Membranous Nephropathy Presenting With Subsequent Autoimmune Nodopathy. (PubMed, Kidney Med) - Sep 26, 2026 - "Intensive immunosuppressive treatment including methylprednisolone, cyclophosphamide, plasmapheresis, intravenous immunoglobulins, and rituximab led to significant neurological improvement and seronegativity for anti-CNTN1 antibodies. It underscores the clinical importance of screening for novel antibodies in phospholipase A2 receptor--negative MN patients, particularly anti-CNTN1 when neurological symptoms develop. This report supports aggressive immunosuppression tailored to antibody-mediated disease and suggests anti-CNTN1 titers as a biomarker for monitoring therapeutic response."
Journal • Glomerulonephritis • Immunology • Nephrology • Pain • Renal Disease • CNTN • CNTN1
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Anne-Els van de Logt; Hanna Debiec; Karlien Mul; Pierre Ronco; Ruben Visch; Shoko Vos; Tom Nijenhuis
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