Glomerular Histiocytosis with Monoclonal IgG Kappa Deposits: An Unusual Presentation of Monoclonal Gammopathy of Renal Significance (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #SA-PO0746; Pres time: Oct 24, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "He was given steroids, rituximab, and avacopan, but after 8 months UPCR had risen to 6 g/g and creatinine to 1.6 mg/dL. A. PAS 400x: mesangial and endocapillary hypercellularity, intracapillary histiocytes B. Paraffin IF: granular capillary loop IgG kappa light chain restriction C. EM: non-crystalline intracellular inclusions and electron dense deposits within histiocytes D. IHC for CD163: confirms the presence of histiocytes"
Glomerulonephritis • Monoclonal Gammopathy • Nephrology • Renal Disease • CD163 • CD68
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Guilherme Gomide Almeida; Brittany Heady; Jay R. Seltzer; Nidia Cordeiro Messias; Nathaniel Reisinger
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