Pegcetacoplan for 76 Weeks Maintains Proteinuria Reduction and Stabilizes Kidney Function in C3 Glomerulopathy or Primary Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN) (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #SA-OR054; Pres time: Oct 24, 2026; 05:50 PM - 06:00 PM; Location: Mile High Ballroom 4A, Convention Center; P3 | "Conclusion Rapid, significant, and sustained proteinuria reduction and stabilized eGFR occurred with 76 wks of pegcetacoplan, with no new safety signals. The IFTA subgroup analysis highlights eGFR stabilization on pegcetacoplan may be strongest in patients with ≤25% IFTA, suggesting a benefit from early detection and targeted treatment."
Complement-mediated Rare Disorders • Fibrosis • Glomerulonephritis • Immunology • Lupus Nephritis • Nephrology • Renal Disease
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Carla M. Nester; Andrew S. Bomback; María Gema Ariceta Iraola; Yahsou Delmas; Bradley P. Dixon; Daniel P. Gale; Larry A. Greenbaum; Seung Hyeok Han; Nicole Isbel; Christoph Licht; Antonio Mastrangelo; Masashi Mizuno; Maria Izabel Neves de Holanda; Matthew C. Pickering; Giuseppe Remuzzi; Nicole Van De Kar; Marina Vivarelli; Patrick D. Walker; Dean Wallace; Daniel Zecher; Moglie Le Quintrec; Yael Borovitz; Nabil Melhem; Fadi Fakhouri
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