Paraneoplastic Minimal Change Disease as an Expanded Spectrum of Monoclonal Gammopathy of Renal Significance in Chronic Lymphocytic Leukemia (CLL) with JAK2-Mutated Myeloproliferative Neoplasm (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO1246; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Despite high dose IV methylprednisolone followed by oral corticosteroids, the patient remained dialysis-dependent without renal recovery. The absence of immune complex deposition and failure to respond to corticosteroids suggest a cytokine-mediated podocytopathy rather than classic immune complex MGRS. These findings expand the spectrum of MGRS to include non-immune complex MCD and underscore the importance of recognizing refractory cases in patients with hematologic disorders, where early clone-directed therapy such as rituximab may be required for renal recovery where corticosteroids alone are insufficient."
Chronic Lymphocytic Leukemia • Glomerulonephritis • Hematological Malignancies • Hepatitis B • Hepatitis C • Hepatology • Human Immunodeficiency Virus • Immunology • Infectious Disease • Inflammatory Arthritis • Leukemia • Monoclonal Gammopathy • Myeloproliferative Neoplasm • Nephrology • Renal Disease • Rheumatoid Arthritis • JAK2
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Anam Naseem; Stanley Yong; Imtiaz Imam; Manzoor Rather
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