Use of Pegcetacoplan in a Pediatric Patient with ESRD to Prevent Recurrence of C3 Glomerulonephritis After Kidney Transplantation (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0935; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "She restarted pegcetacoplan about one month prior to renal transplant and then underwent living unrelated kidney transplant with thymoglobulin induction and rituximab infusions...Discussion C3 inhibitors such as pegcetacoplan have been shown to reduce proteinuria and disease activity in patients with C3GN, but had not previously been used to prevent disease recurrence post-transplant. We demonstrate that pegcetacoplan may help prevent disease recurrence in patients with C3GN requiring renal transplantation."
Clinical • Atypical Hemolytic Uremic Syndrome • Chronic Kidney Disease • Complement-mediated Rare Disorders • Glomerulonephritis • Hematological Disorders • Lupus Nephritis • Nephrology • Pediatrics • Renal Disease • Transplantation
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Elliott Huang; Hilda E. Fernandez; Kenneth V. Lieberman
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