Relapsing and Remitting Pattern of Primary Membranous Nephropathy (MN) with Coexistent Thrombotic Microangiopathy (TMA) After Allogenic Hematopoietic Stem Cell Transplantation (HSCT) in a Patient with Acute Myeloid Leukemia (AML) (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO1257; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Case Description A 52-year-old woman with nephrolithiasis, ADHD, hemorrhoids, and APML diagnosed in 2023 underwent induction chemotherapy with idarubicin/cytarabine, later transitioned to HyperCVAD-1B because of neutropenic fever and pneumonia. She subsequently underwent matched unrelated donor allogeneic stem cell transplantation following total body irradiation/cyclophosphamide conditioning. Her post-transplant course was complicated by severe mucositis requiring analgesia, tacrolimus for GVHD prophylaxis, and CMV reactivation treated successfully with valganciclovir...On November 17, 2025, she presented with altered mental status concerning for hepatic encephalopathy and was treated with lactulose and rifaximin...Rituximab led to marked improvement in renal function and proteinuria...We present a rare case of chronic GVHD-associated membranous nephropathy with overlapping renal-limited TMA and a relapsing-remitting course of MN. This case highlights the value of..."
Clinical • Acute Myelogenous Leukemia • Acute Promyelocytic Leukemia • ADHD (Impulsive Aggression) • Attention Deficit Hyperactivity Disorder • Bone Marrow Transplantation • Cardiovascular • Chronic Graft versus Host Disease • CNS Disorders • Febrile Neutropenia • Gastroenterology • Gastrointestinal Disorder • Glomerulonephritis • Graft versus Host Disease • Hematological Malignancies • Hepatic Encephalopathy • Hepatology • Immunology • Infectious Disease • Leukemia • Mucositis • Nephrology • Pneumonia • Portal Hypertension • Renal Calculi • Renal Disease • Respiratory Diseases • Transplantation • CDH23 • PCDH
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Jawad Mir; Mariam Charkviani; Huma Fatima
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