Bilateral cytomegalovirus retinitis in the setting of acquired lymphopenia following administration of bendamustine. (PubMed, Retin Cases Brief Rep) - Sep 24, 2026 - "Bendamustine can cause profound lymphopenia with reduced CD4 T-cell levels; risk of herpes virus retinitis is elevated in the setting of such immunosuppression. In HIV-negative patients, there is no specific treatment to raise the CD4 count. Prompt initiation and continued administration of systemic and local antiviral treatment can lead to disease control and preservation of vision while awaiting immune reconstitution."
Journal • Cytomegalovirus Infection • Follicular Lymphoma • Genetic Disorders • Hematological Disorders • Hematological Malignancies • Human Immunodeficiency Virus • Infectious Disease • Lymphoma • Non-Hodgkin's Lymphoma • Ocular Inflammation • Oncology • Ophthalmology • Retinal Disorders • CD4
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Christine I Clavell; Ghassan R Ghorayeb; James P Dossett; Kevin T Eid
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