T-Cell Large Granular Lymphocytic Leukemia (T-LGL) as a Potential Trigger for Collapsing Glomerulopathy in a Patient with an APOL1 High-Risk Genotype (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0722; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Cancer treatment included methotrexate, rituximab, and subsequently clinical trial enrollment. 24 months from presentation, with controlled LGL, has a creatinine 1.4-1.6 mg/dL, proteinuria 2-4 g/day before initiation of sparsentan...Prior reports of paraneoplastic glomerular disease have been limited by lack of genetic testing. In the absence of viral infections or autoimmune disease, a search for underlying hematologic malignancy in patients with collapsing FSGS may be considered."
Clinical • Focal Segmental Glomerulosclerosis • Glomerulonephritis • Hematological Malignancies • Human Immunodeficiency Virus • Immunology • Infectious Disease • Leukemia • Nephrology • Renal Disease • T-Cell Large Granular Lymphocyte Leukemia
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Omid Vadpey; Anatoly Urisman; Divya Ravi; Chenyin He; Gabriel Loeb; Raymond K. Hsu; Christopher R. Showers
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