Severe Crescentic PR3-ANCA Glomerulonephritis with Prominent IgG4+ Plasma Cells: Diagnostic and Therapeutic Implications (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0765; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "In severe renal AAV with markedly reduced eGFR and extensive crescent formation, current KDIGO guidance supports cyclophosphamide based induction, given limited data for rituximab in severe cases of crescentic glomerulonephritis. Plasma cell rich interstitial linflammation, hematoxylin and eosin stain, magnification 400X. Increased IgG4 positive plasma cells noted by immunohistochemistry, magnification 400X."
ANCA Vasculitis • Fibrosis • Glomerulonephritis • Immunology • Inflammation • Lupus Nephritis • Nephrology • Renal Disease • Vasculitis
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Nimrah H. Imam; Anita Kamarzarian; Vardan Dagstanyan; Golriz Jafari; Phuong-Chi T. Pham; Jean Hou
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