Refractory Anti-GBM Disease with Persistent Serologic Activity and Ultrastructural GBM Remodeling (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0748; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Initial steroids, cyclophosphamide, and plasma exchange improved respiratory but not renal status. Due to persistent serologic activity, therapy was escalated with rituximab, achieving sustained B-cell depletion, alongside C5 complement inhibition...Persistent serologic activity despite partial renal recovery suggests a dissociation between antibody levels and renal injury. This case highlights persistent anti-GBM serologic activity with chronic ultrastructural GBM remodeling despite intensive therapy, expanding the spectrum of structural lesions observed in refractory anti-GBM disease."
Glioblastoma • Glomerulonephritis • Hematological Disorders • Lupus Nephritis • Nephrology • Renal Disease
|
|
Duhlicher Vera; Ionela Lazar; Stefan Nicolaie Lujinschi; Gener Ismail
|