Is Antibody Clearance Enough? Immunologic Remission Frequently Fails to Translate into Proteinuria Resolution in Phospholipase A2 Receptor (PLA2R)-Associated Membranous Nephropathy (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0810; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Rituximab use was significantly higher among immunological responders (60% vs. 34%, p=0.009)...Dependence on current ELISA–only thresholds (<14 RU/mL) may overestimate antibody clearance; adding negative immunofluorescence improves complete remission prediction. These findings challenge current surrogate endpoints and underscore the need to recalibrate immunological remission definitions in MN."
Clinical • Chronic Kidney Disease • Glomerulonephritis • Renal Disease
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Nilang G. Patel; Naman Gupta; Scott Silvey; Jason M. Kidd; Ambarish Athavale
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