Clinical phenotypes, endotypes, and biomarker profiles of immediate rituximab hypersensitivity reactions: a prospective pharmacovigilance study. (PubMed, Front Allergy) - Sep 19, 2026 - "IRRs were the most common phenotype and occurred exclusively during the first RTX cycle. Skin testing, ADA detection, and serum IL-6 measurement may contribute to endotype characterization, although larger prospective studies are needed to establish their diagnostic utility."
Adverse events • Biomarker • Journal • Immunology • Inflammation • IFNG • IL6
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Apinya Chungcharoenpanich; Chavachol Setthaudom; Jettanong Klaewsongkram; Kumutnart Chanprapaph; Narapong Yotinnoratham; Nattakirana Tongdee; Nichapha Dechapaphapitak; Pungjai Mongkolpathumrat; Ratchaya Lertnawapan; Sananya Khamkaew; Silada Kanokrungsee; Supa Oncham; Supornchai Onpun; Supranee Buranapraditkun; Wannada Laisuan
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