Bardoxolone methyl exerts an inhibitory effect on respiratory syncytial virus infection by downregulating IL-6 via the IKKβ/NF-κB signaling pathway. (PubMed, Microbiol Spectr) - Sep 19, 2026 - "Importantly, our findings suggest that BXM acts, at least in part, by reducing IL-6-related inflammatory signaling, which is closely associated with RSV disease severity. These results provide experimental evidence supporting BXM as a promising candidate for further development against RSV infection and offer insight into a potential host-targeted therapeutic strategy."
Journal • Infectious Disease • Inflammation • Respiratory Diseases • Respiratory Syncytial Virus Infections • IL6
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Bingyao Wang; Daishun Liu; Hongping Wang; Jin Nie; Ling Zhang; Xinran Tan; Xunping Wu; Zhu Li
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