ABO-incompatible kidney transplantation without desensitization - A German multicenter cohort study (TTS 2026) - Sep 17, 2026 - Pres time: Sep 23, 2026; 09:25 AM - 09:35 AM; Location: Cockle Bay 1; 420; "Current desensitization protocols typically combine plasma exchange or immunoadsorption (PLEX) with rituximab (RTX)...Maintenance immunosuppression mainly consisted of basiliximab induction followed by tacrolimus, mycophenolate mofetil, and steroids; approximately 20% received IVIG... In carefully selected patients with low baseline ABO isoagglutinin titers, ABOi-LDKT without desensitization appears safe and provides comparable short-term graft function, rejection rates, and patient/graft survival. Avoiding RTX may reduce severe infections requiring hospitalization."
Clinical • Antibody-mediated Rejection • Infectious Disease • Transplantation
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Ulrich Pein1; Anja Muehlfeld2; Lutz Liefeldt3; Klemens Budde3; Rolf Weimer4; Louise Benning5; Christine Kurschat6; Stefan Reuter7; Nils Lachmann8; Martina Koch9
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