Rituxan (rituximab) - Roche
doxorubicin hydrochloride - Generic mfg.
cyclophosphamide - Generic mfg.
Columvi (glofitamab-gxbm) - Roche
prednisone - Generic mfg.
Polivy (polatuzumab vedotin-piiq) - Roche
A multicenter phase II study of glofitamab plus polatuzumab-R-CHP for patients with diffuse large B-cell lymphoma. (PubMed, Blood) - Oct 7, 2026 - P2 | "In this phase II trial, we evaluated the addition of the CD3xCD20 bispecific antibody, glofitamab (glofit) to polatuzumab, rituximab, cyclophosphamide, doxorubicin, and prednisone (pola-R-CHP) in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL) and an international prognostic index (IPI) ³ 2. These data support further evaluation of this regimen. NCT05800366." 
Journal • P2 data • B Cell Lymphoma • Diffuse Large B Cell Lymphoma • Hematological Malignancies • High-grade B-cell lymphoma • Lymphoma • Non-Hodgkin's Lymphoma • Oncology • BCL2 • BCL6
http://www.ncbi.nlm.nih.gov/pubmed/42837325
 
Alvaro J Alencar; Ann S LaCasce; Austin I Kim; Caron A Jacobson; Christine E Ryan; Clare Phinney; Craig H Moskowitz; David A Qualls; David C Fisher; Eric D Jacobsen; Erin M Parry; Gottfried von Keudell; Inhye E Ahn; Jennifer L Crombie; Jennifer R Brown; Juan Pablo Alderuccio; Juniper Mai; Matthew S Davids; Megan Forsyth; Michele Stanchina; Oreofe O Odejide; Philippe Armand; Reid W Merryman; Robert Redd; Russ A Kuker; Sandra Re
 
Oct 7, 2026
 
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