Durable Third Kidney Allograft Function in Jeune Syndrome with Calculated Panel Reactive Antibody (cPRA) 99%-100% and Donor-Specific Antibody (DSA) Positivity (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #TH-PO1040; Pres time: Oct 22, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "A 2003 living-unrelated transplant was complicated by transplant-ureter reflux with recurrent pyelonephritis, ureteroureterostomy, biopsy-documented CAN, suspected CNI toxicity, hypertensive emergency, zoster treated with IV valacyclovir complicated by AKI/metabolic acidosis, severe pancreatitis, and return to PD in 2013...In 2015, she received a deceased-donor kidney transplant with TPE ×4, thymoglobulin, steroids, tacrolimus, and rituximab...Second-graft loss was multifactorial, underscoring the value of integrated longitudinal review in complex retransplant candidates. Key teaching points: Jeune-associated renal disease can require repeat transplantation; durable function is achievable with individualized high-risk protocols; and adult syndromic recipients need multidisciplinary urologic, hepatobiliary, pancreatic, and skeletal care."
Fibrosis • Hematological Disorders • Herpes Zoster • Immunology • Metabolic Disorders • Nephrology • Pancreatitis • Transplant Rejection • HLA-DQA1
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Diego Tijerina; Yassin EL-Najjar; Mary-Joe Touma; Mourad Alsabbagh
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