Monoclonal Membranous Nephropathy as the Initial Manifestation of Chronic Lymphocytic Leukemia (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #TH-PO1151; Pres time: Oct 22, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Case Description A 76 yo male with medical history of hypertension on lisinopril and nephrolithiasis, developed foamy urine and was diagnosed with nephrotic syndrome that prompted referral to nephrology clinic...The patient received 2 cycles of 4 doses each of IV rituximab (total of 8 doses of IV rituximab) between December 2025 and February 2026. Furthermore, he was started on oral prednisone taper with starting dose of 40 mg daily, for its lymphodepleting effect...In our case, the pathophysiology of renal injury was mediated by monoclonal immunoglobulin toxicity, originating from the underlying CLL. It is of utmost importance to know that paraneoplastic glomerulopathy may precede cancer diagnosis, and treating the malignancy is the cornerstone of therapy."
Chronic Lymphocytic Leukemia • Fibrosis • Genito-urinary Cancer • Glomerulonephritis • Hematological Malignancies • Hypertension • Immunology • Leukemia • Lymphoma • Nephrology • Non-Hodgkin's Lymphoma • Prostate Cancer • Renal Calculi • Renal Disease • Solid Tumor
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Hunter T. Reed; Akram Audi
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