Fulminant Crescentic IgAN with Renal-Limited Thrombotic Microangiopathy Progressing to Kidney Failure Despite Complement Inhibition (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #TH-PO0536; Pres time: Oct 22, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Due to the rapidly progressive course, persistent nephrotic-nephritic syndrome, recurrent gross hematuria, resistant hypertension, and severe hypervolemia, immunosuppressive therapy was progressively intensified with high-dose corticosteroids, cyclophosphamide, rituximab, plasma exchange, and complement inhibition with ravulizumab. Progression to kidney failure despite maximal immunosuppression, plasma exchange, and complement inhibition shows the lack of clear therapeutic options in this setting. Fulminant crescentic IgAN with renal-limited TMA may progress to kidney failure despite maximal therapy, highlighting the need for better markers to guide treatment."
Cardiovascular • Glomerulonephritis • Hypertension • IgA Nephropathy • Lupus Nephritis • Nephrology • Renal Disease • Vasculitis
|
|
Ionela Lazar; Ioana Borjoiu; Stefan Nicolaie Lujinschi; Gener Ismail
|