Rituximab therapy achieves comparable remission to cyclophosphamide in ANCA-associated vasculitis with severe kidney involvement. (PubMed, Clin Kidney J) - Sep 16, 2026 - "At 12 months, there was no significant difference in the proportion of patients with independent renal function (CYC 65% vs RTX 56%; P = .582), eGFR was similar between CYC and RTX patients (28 vs 31 mL/min/1.73 m2; P = .439), and 94% of the CYC cohort were alive compared with 83% of the RTX cohort (P = .068). RTX with steroids is comparable to CYC with steroids for successfully inducing remission in AAV with severe renal involvement."
Journal • ANCA Vasculitis • Vasculitis
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Azm Ul Hussain; Dimitrios Chanouzas; Joshua Harridine; Kashif Eqbal; Lee Quill; Lorraine Harper; Nishant Chaudhari
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