Precision-guided therapy in dialysis-dependent classic hairy cell leukemia: a case report. (PubMed, Front Oncol) - Sep 16, 2026 - "We present a novel case of a 43-year-old man on chronic hemodialysis secondary to suspected autosomal dominant polycystic kidney disease diagnosed with classic BRAF V600E-mutated HCL, treated with low-dose vemurafenib in combination with anti-CD20 therapy...This report highlights the feasibility and efficacy of BRAF-targeted therapy combined with an anti-CD20 antibody in a young dialysis-dependent HCL patient, expanding therapeutic options for this high-risk population. Further prospective studies and case series are needed to guide management in this unique clinical context."
Journal • Autosomal Dominant Polycystic Kidney Disease • Chronic Kidney Disease • Fibrosis • Genetic Disorders • Hairy Cell Leukemia • Hematological Disorders • Hematological Malignancies • Immunology • Leukemia • Nephrology • Oncology • Polycystic Kidney Disease • Renal Disease
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Eric J Vick; Madhu Bhargavi Chandra; Sindhusha Veeraballi
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