Beyond Chronic Rhinosinusitis: Multisystem Granulomatosis With Polyangiitis Presenting With Cavitary Pulmonary Nodules and Sinonasal Destruction. (PubMed, Cureus) - Sep 15, 2026 - "High-dose systemic glucocorticoids and rituximab-based induction therapy were initiated with Pneumocystis jirovecii pneumonia prophylaxis and multidisciplinary rheumatology, otolaryngology, pulmonology, and nephrology follow-up. This case is not presented as a unique manifestation of GPA but as an educational reminder that chronic rhinosinusitis becomes a diagnostic trap when accompanied by epistaxis, septal destruction, pulmonary cavitation, purpura, neuropathic symptoms, or urinary abnormalities. Earlier recognition of this pattern may prevent irreversible organ damage."
Journal • Cardiovascular • Hematological Disorders • Infectious Disease • Nephrology • Oncology • Otorhinolaryngology • Pneumonia • Rare Diseases • Renal Disease • Respiratory Diseases • Rheumatology • Sinusitis • Vasculitis
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Anthony Nazur; Daniela Delphus; Emily Reinoso; Josue P Boutros; Kian Memari; Lissette P Lazo; Maria J Morales; Peter Cohen; Shane Williams
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