microRNA expression in macrophages regulates antibody-dependent effector function and B cell lymphoma therapy. (PubMed, Cancer Res Commun) - Oct 15, 2026 - "Combination of high microRNA 142-5p and CD206 expression correlated with a reduction in progression free survival following standard Rituximab containing chemotherapy regimens in 38 patients. Together these studies indicate the potential of targeting microRNA to repolarise macrophages and improve treatment success."
IO biomarker • Journal • B Cell Lymphoma • Chronic Lymphocytic Leukemia • Diffuse Large B Cell Lymphoma • Hematological Malignancies • Lymphoma • Non-Hodgkin's Lymphoma • Oncology • CD163 • CD40 • CD47 • IFNG • IL10 • IL13 • IL4 • MIR142 • MRC1 • TGFB1
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Andrew Davies; Jemma Longley; Lekh N Dahal; Margaret Ashton-Key; Mark S Cragg; Matthew J Carter; Peter W M Johnson; Robert Kemp; Rosanna C Smith; Russell B Foxall; Stephen A Beers; Stephen Thirdborough
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