Fire and Drought: Anti-N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis Presenting with Diabetes Insipidus (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0883; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Case Description A 36-year-old male with ESKD post-kidney transplant and NMDAR encephalitis (treated with IVIG and rituximab) presented to the clinic with hypernatremia of 162 and AKI on allograft CKD...DDAVP was initiated with some improvement in urine osmolarity but persistent hypernatremia...In anti-NMDAR encephalitis, low urine osmolality with hypernatremia should prompt CDI evaluation rather than assuming decreased intake alone. Renal transplant recipients may have intrinsic concentrating deficits due to denervation and ischemia-reperfusion injury, which must be considered when interpreting urine osmolality for CDI diagnosis."
Cardiovascular • Chronic Kidney Disease • CNS Disorders • Inflammation • Metabolic Disorders • Reperfusion Injury
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Priyal Sakhuja; Kishan Rao; Aiswarya Menon; Joshua L. Rein; Jaime Uribarri; Samira S. Farouk
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