Not Your Average Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH): Anti-LGI1 Encephalitis (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0868; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "He was diagnosed with SIADH and focal seizures and started on levetiracetam, 1L liter fluid restriction, NaCl 3g TID, demeclocycline 300mg BID, urea powder 15g BID, and tolvaptan 15mg QOD...He was started on valproic acid and treated with five days of IV methylprednisolone and rituximab infusion for LGI1 autoimmune encephalitis...2. The hyponatremia is associated with elevated urine osmolarity and urine sodium consistent with SIADH.The exact cause is unclear; LGI1 is expressed in mice in the hypothalamus (suggestive of ADH secretion) but also in uncharacterized renal tubules."
Addiction (Opioid and Alcohol) • Anorexia • Brain Cancer • Cardiovascular • CNS Disorders • Epilepsy • Glioma • Heart Failure • Immunology • Migraine • Solid Tumor • Type 2 Diabetes Mellitus
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Sara Adelina Cuadra Aruguete; Benjamin S. Ko
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