Nephrin Autoantibodies in Idiopathic Nephrotic Syndrome Represent a Disease Endotype Associated with Good Long-Term Prognosis (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0633; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Nephrin autoantibody titres were also higher in patients who responded to steroids (p=0.024), and who did not require Rituximab in their disease course (p=0.047). Conclusion Elevated nephrin autoantibody titres are associated with MCD and eventual immunological remission, as well as greater drug-responsiveness. Nephrin autoantibody-mediated disease may constitute a disease endotype that represents the archetypical childhood-onset nephrotic syndrome."
Chronic Kidney Disease • Focal Segmental Glomerulosclerosis • Glomerulonephritis • Nephrology • Renal Disease
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Chang-Yien Chan; Li Ling Quek; Sharon Teo; Mya Than; Yew Weng Perry Lau; Kar Hui Ng; Hui Kim Yap; Liangjian Lu
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