DYNAMICS AND CLINICAL IMPACT OF CLONAL HEMATOPOIESIS IN DIFFUSE LARGE B-CELL LYMPHOMA THROUGH MULTI-COMPARTMENT GENOMIC PROFILING (SIE 2026) - Oct 6, 2026 - Abstract #C065; Pres time: Sep 22, 2026; 03:40 PM - 05:10 PM; Location: HALL 1; "R-CHOP promotes CH clonal expansion, including early PP- M1D emergence. While PB-CH did not significantly impact survival, TI-DNMT3A mutations are an independent adverse prognostic factor for PFS and OS."
Clinical • B Cell Lymphoma • Diffuse Large B Cell Lymphoma • Hematological Malignancies • Lymphoma • Non-Hodgkin's Lymphoma • DNMT3A • PPM1D • TET2
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N. Maher1,2; S. Mouhssine2; M. Almasri2; C. Cosentino2; L. Cividini2; R. Bruna2; R. Tavarozzi1; G. M. Assanto3; R. Dondolin2; M. Bellia2; M. C. La Licata2; J. Nabki2; B. Al Deeban2; J. Ghanej2; F. Maiellaro2; M. Leutner5; A. Andorno4; F. Mercalli4; A. M. Mahmoud2; N. M. Diop2; C. Deambrogi2; S. Rasi2; A. Di Rocco3; I. Del Giudice3; L. Donzelli3; R. Foà3; R. L. Boldorini4; M. Ladetto1; G. Gaidano2; R. Moia2
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