Rituxan (rituximab) - Roche
Jakafi (ruxolitinib) - Incyte
etoposide IV - Generic mfg.
Hemophagocytic Lymphohistiocytosis Thought to Be due to Undifferentiated Connective Tissue Disease Treated With Ruxolitinib: A Case Report. (PubMed, Case Rep Rheumatol) - Oct 20, 2026 - "A number of conventional therapies did not show clear benefit, including etoposide, high-dose steroids, rituximab, and plasmapheresis. Ruxolitinib has shown some success in treating HLH in preliminary studies, but it is still considered a salvage therapy. This case illustrates the successful use of ruxolitinib in a patient with HLH likely due to undifferentiated connective tissue disease." 
Journal • Hemophagocytic lymphohistiocytosis • Immunology • Rare Diseases • Rheumatology
http://www.ncbi.nlm.nih.gov/pubmed/42894865
 
Emily Vachon; Heena Birbal Jain; Suzanna Kitten
 
Oct 20, 2026
 
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