When the Kidneys Speak Loudest: Atypical Presentation of c-ANCA Vasculitis (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #PUB132; "Case Description A 74-year-old male with hypertension initially presented to urologist with hematuria attributed to renal stones and urinary tract infection and was treated with levofloxacin. He then developed a facial rash and was prescribed valacyclovir by his dermatologist, but the culture was later negative for HSV...Given worsening renal function and active urinary sediment, he was started empirically on intravenous Solumedrol 1 g for three days, suspecting acute glomerulonephritis...He was transitioned to oral prednisone 60 mg daily and received IV rituximab 1 g, with the next dose in two weeks. Avacopan was considered but deferred due to pharmacy issues...Current guidelines recommend induction therapy with glucocorticoids combined with rituximab or cyclophosphamide. Rituximab is increasingly chosen due to similar efficacy and a better safety profile. This case highlights that delayed diagnosis of ANCA vasculitis in some patients can present as severe..." Acute Kidney Injury • ANCA Vasculitis • Cardiovascular • Fibrosis • Glomerulonephritis • Hypertension • Immunology • Infectious Disease • Lupus Nephritis • Nephrology • Ophthalmology • Renal Calculi • Renal Disease • Urolithiasis • Vasculitis
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Vishnu Vardhan Karrothu; Revathi Kudithi; Damodar R. Kumbala
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