Antigen-Specific Differences in Membranous Nephropathy: Lower Response and Higher Relapse Rates in Phospholipase A2 Receptor (PLA2R)-Associated Disease (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #FR-PO0804; Pres time: Oct 23, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "Rituximab as initial therapy was associated with higher complete response (aHR 2.48, 95%CI 1.16-5.30) and lower relapse (aHR 0.17, 95%CI 0.03-0.98). Conclusion PLA2R-associated MN is linked to lower complete response and higher relapse risk than other antigen specificities. Nearly 40% of patients lacked identifiable PLA2R or NELL1, highlighting the need for further antigen evaluation in this cohort."
Glomerulonephritis • Renal Disease • NELL1
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Julio Cesar Santos; Héctor Benjamín Garcia; Alejandro Quiñonez-Flores; Melvin Barish Matías Martinez; Andre Mendez; Juan-Esteban Reyes-Moreno; Norma O. Uribe-Uribe; Juan M. Mejia-Vilet; María Fernanda Zavala Miranda
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