IL-17A Induces Chondrocyte Senescence via the STAT3-OPA1-mtROS Axis in Temporomandibular Joint Osteoarthritis. (PubMed, Oral Dis) - Oct 2, 2026 - "IL-17A induces chondrocyte senescence by promoting mitochondrial dysfunction through a STAT3-OPA1-mtROS-dependent axis, and IL-17A may serve as a therapeutic target for the treatment of TMJ-OA."
Journal • Immunology • Metabolic Disorders • Ocular Inflammation • Osteoarthritis • Pain • Rheumatology • IL17A • OPA1 • STAT3
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Chunyan Zhang; Congdi Zhang; Jiejun Shi; Linghan Qu; Mengjie Wu; Mengqi Zhu; Minjuan Shen; Qianming Chen; Yangyang Zhang; Ying Wang; Zuping Wu
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