Pluvicto (lutetium Lu 177 vipivotide tetraxetan) - Novartis
Preclinical Evaluation of ¹⁷⁷Lu-PSMA-XT for Targeted Treatment of Prostate Cancer with Moderate PSMA Expression (EANM 2026) - Sep 29, 2026 - Abstract #EP-0178; "Aim/Introduction: Current ¹⁷⁷Lu-PSMA-617 therapy for metastatic castration-resistant prostate cancer is limited by insufficient tumor uptake, rapid clearance, and the need for high doses and repeated cycles... ¹⁷⁷Lu-PSMA-XT showed high binding affinity, improved tumor uptake, and prolonged retention, indicating therapeutic potential for prostate cancer with moderate PSMA expression." 
Preclinical • Castration-Resistant Prostate Cancer • Genito-urinary Cancer • Oncology • Prostate Cancer • Solid Tumor • FOLH1
https://www.sciencedirect.com/science/article/pii/S3051291326002855?via%3Dihub
 
Y. Liu; R. Xue; X. Zhang; B. Xu; H. Wang; R. Wang; J. Zhang
 
Sep 29, 2026
 
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