Functional Mitral Regurgitation Trajectories in CRT-Treated HFrEF During Medical Therapy Optimization: Association with Reverse Remodeling. (PubMed, J Clin Med) - Oct 17, 2026 - "These findings describe parallel longitudinal changes in MR severity and cardiac structure within a combined device- and pharmacological-treatment setting. The observed changes cannot be disentangled from ongoing CRT-mediated remodeling, concomitant GDMT, changes in loading conditions, or other time-dependent factors and cannot be attributed specifically to sacubitril/valsartan."
Journal • Cardiovascular • Heart Failure
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Bogdan Enache; Constantin-Tudor Luca; Liviu Cirin; Maria-Laura Cr?ciun; Mirela Vîrtosu; Silvia Luca
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