Jakafi (ruxolitinib) - Incyte
Potential Benefit of Ruxolitinib in Suspected Ocular and Neurological Transplant-Associated Thrombotic Microangiopathy After Allogeneic Stem Cell Transplantation: A Case Report and Review. (PubMed, Clin Case Rep) - Oct 2, 2026 - "The condition was refractory to standard therapies; neurological improvement was temporally associated with ruxolitinib initiation, suggesting a possible GVHD overlap. This report supports a multidisciplinary approach to complex post-transplant endothelial injury and supports further investigation of JAK inhibition in selected cases." 
Journal • Bone Marrow Transplantation • Graft versus Host Disease • Immunology • Retinal Disorders • Transplantation • Transplantation Associated Thrombotic Microangiopathy
http://www.ncbi.nlm.nih.gov/pubmed/42819691
 
Adrien Lefèvre; Antoine Arandilla; Antoine Bonnevalle; Bertrand Bourre; Dominique Penther; Fabrice Jardin; Gaëtan Sauvetre; Lise-Marie Pillet; Maximilien Grall; Mustafa Alani; Paul Goupillou; Sophie Porcheron; Sydney Dubois; Vincent Camus
 
Oct 2, 2026
 
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