Xofigo (radium Ra-223 dichloride) - Bayer
Pluvicto (lutetium Lu 177 vipivotide tetraxetan) - Novartis
Severe Cytopenias Following Radioligand Therapy: A Real-World Analysis. (PubMed, Clin Genitourin Cancer) - Oct 19, 2026 - "This large, real-world study demonstrated that Radium-223 is associated with significantly higher risk of severe cytopenias compared with 177Lu-PSMA-617. Findings may inform appropriate patient selection, and sequencing of radiopharmaceutical therapy. Future studies aimed at evaluating the bone marrow environment may further elucidate the potential for clonal hematopoiesis and therapy-related myeloid neoplasms." 
Journal • Real-world evidence • Castration-Resistant Prostate Cancer • Genito-urinary Cancer • Hematological Disorders • Hematological Malignancies • Neutropenia • Oncology • Prostate Cancer • Solid Tumor • Thrombocytopenia
http://www.ncbi.nlm.nih.gov/pubmed/42892238
 
Benyamin Yaniv; Kriti Mittal; Mrinal M Patnaik; Petros Grivas; Robert Yuan; Shyam A Patel
 
Oct 19, 2026
 
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