Optimal Reconstruction Parameters for Quantitative 177 Lu SPECT/CT Imaging in Absorbed Dose Estimation (EANM 2026) - Sep 29, 2026 - Abstract #OP-643; Pres time: Oct 20, 2026; 09:45 AM - 11:15 AM; Location: Hall K; "Aim/Introduction: 177Lu-DOTATATE dosimetry in targeted radionuclide therapy relies on quantitative SPECT/CT imaging, and reconstruction algorithms affect absorbed dose estimation... Optimization of reconstruction parameters achieved quantitative convergence in the MRTDosimetry phantom. When applied to clinical datasets, absorbed dose estimates showed good agreement between OSEM and MAP methods. These results support the feasibility of standardized absorbed dose estimation based on quantitative SPECT/ CT imaging."
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N. Akiya 1; N. Miyaji 1; T. Yamao 1; K. Wachi 1; M. Masubuchi 1, 2; A. Komatsu 1; T. Horikawa 1; Y. Ogane 1; O. Kanno 1; S. Mashiko 1; A. Oishi 3; M. Morimoto 3; Y. Yamamoto 4; Y. Nishiyama 4; K. Miwa 1
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