A Full Monte Carlo Reconstruction Algorithm for Improved Precision via Dual-Photopeak Lu-177 SPECT Imaging (EANM 2026) - Sep 29, 2026 - Abstract #OP-091; Pres time: Oct 18, 2026; 09:45 AM - 11:15 AM; Location: Hall B; "Performance was additionally assessed using five count-resampled noise realizations from a clinical [Lu-177]Lu-DOTATATE patient dataset acquired over two bed positions... Dual-photopeak full Monte Carlo reconstruction substantially improves precision in Lu-177 SPECT imaging while maintaining comparable quantitative accuracy. By incorporating both the 113 keV and 208 keV photopeak windows within a unified physics-based framework, the method provides a practical pathway toward shorter acquisition times and imaging of lower activities on conventional NaI-based SPECT systems."
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L. Polson 1; F. J. Wilson 1; S. Graves 2
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