Fibroblast Growth Factor 2 Enhances Contraction of Arterioles in the Medulla Oblongata and the Basilar Artery in Mice With Chronic Kidney Disease. (PubMed, Acta Physiol (Oxf)) - Oct 2, 2026 - "CKD enhances cerebrovascular contractile responses to vasoconstrictors, and this effect is mediated by activation of the FGF2 pathway. Targeting the FGF2 pathway may provide treatment of cerebrovascular dysfunction in CKD."
Journal • Preclinical • Chronic Kidney Disease • Nephrology • Renal Disease • EDN1 • FGF2 • FGFR
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Andreas Patzak; Chunxiang Xu; En Yin Lai; Gensheng Zhang; Jianhua Mao; Liang Zhao; Nan Xu; Pontus B Persson; Xingyu Qiu
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