Comparative Analysis of Systemic Complications of Antivascular Endothelial Growth Factor Therapies in Retinal Diseases. (PubMed, J Vitreoretin Dis) - Sep 28, 2026 - " The TriNetX Research Network database was used to identify adults with macular edema secondary to diabetes, retinal vein occlusion, or age-related macular degeneration who received bevacizumab, ranibizumab, or aflibercept (2012-2022) or faricimab (2022-2024). This underscores the importance of tailoring anti-VEGF therapy to patient-specific profiles, particularly in patients with underlying cardiovascular and renal comorbidities. Further studies in lower-comorbidity populations are needed to clarify these associations."
Journal • Age-related Macular Degeneration • Cardiovascular • Cerebral Hemorrhage • Diabetes • Hematological Disorders • Hypertension • Macular Degeneration • Macular Edema • Metabolic Disorders • Myocardial Infarction • Ophthalmology • Retinal Disorders • Retinal Vein Occlusion • Venous Thromboembolism
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Adarsh Mallepally; Esha Mittal; Jessica Randolph; Michelle Lam; Mirataollah Salabati; Raziyeh Mahmoudzadeh
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