Targeting MicroRNA-21 in Chronic Kidney Disease: Lessons from the Lademirsen Story. (PubMed, Med Sci (Basel)) - Sep 25, 2026 - "Future therapeutic strategies will likely require earlier intervention, improved patient selection, robust biomarkers of target engagement, and combination approaches that address the multifactorial nature of CKD. The lessons learned from the lademirsen program may help guide the development of the next generation of RNA therapeutics for kidney disease."
Journal • Review • Chronic Kidney Disease • Fibrosis • Genetic Disorders • Immunology • Inflammation • Metabolic Disorders • Nephrology • Renal Disease • MIR21
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Aleksandar Sic; Aleksandra Kezic; Ana Bontic; Dusan Vicentijevic; Jelena Pavlovic; Marko Baralic; Selena Gajic; Verica Stankovic Popovic
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