Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer

Nubeqa (darolutamide) - Bayer, Orion Corp

enzalutamide - Generic mfg.

Yonsa (abiraterone acetate) - Sun Pharma

Decadron (dexamethasone) - Merck (MSD)

prednisone delayed-release tablet - Generic mfg.

Pluvicto (lutetium Lu 177 vipivotide tetraxetan) - Novartis

docetaxel - Generic mfg.

abiraterone acetate - Generic mfg.

Hemady (dexamethasone tablets) - Dexcel Pharma

cabazitaxel - Generic mfg.

Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer (clinicaltrials.gov) - Oct 2, 2026 - P2/3 | N=432 | Not yet recruiting | Sponsor: ECOG-ACRIN Cancer Research Group
New P2/3 trial • Castration-Resistant Prostate Cancer • CNS Disorders • Genito-urinary Cancer • Oncology • Prostate Adenocarcinoma • Prostate Cancer • Solid Tumor

http://clinicaltrials.gov/ct2/show/NCT07852195

Oct 2, 2026