Monocyte-Mimetic Nanoparticle Delivery of Verteporfin Promotes Plaque-Stabilizing Remodeling in Atherosclerosis. (PubMed, bioRxiv) - Sep 25, 2026 - "Importantly, repeated MoNP-VP administration was well tolerated and elicited no overt systemic toxicity. These findings bridge mechanistic insight and therapeutic efficacy in pre-established plaques by demonstrating that MoNP-VP remodels the inflammatory plaque microenvironment and promotes lesion stabilization, supporting its translational potential as a precision nanotherapy for atherosclerosis." Journal • Atherosclerosis • Cardiovascular • Dyslipidemia • Fibrosis • APOE
|
|
Andrew Zehnder; Christopher L Plaisier; Hui-Chun Huang; Kuei-Chun Wang; Sin-Pei Wu; Ting-Yun Wang
|