Integrative transcriptomics identifies an 18-gene candidate blood-accessible biomarker panel for longitudinal monitoring of spaceflight-induced muscle atrophy. (PubMed, PLoS One) - Oct 8, 2026 - "Integrated drug-gene analysis identified bimagrumab combined with leucine as the top predicted prioritised countermeasure pair (computational Bliss = 2.8)...The unit of analysis was the analytical contrast (spaceflight vs. matched ground control), not the publication. Cross-platform harmonization was performed via gene-level mapping and rank-based normalization."
Biomarker • Journal • Muscular Atrophy • Targeted Protein Degradation • FOXO3 • IGF2
|
|
Hyeon Soo Kim; Jae Ho Shim; Ji Yeon Lee; Jihye Han
|