Bilateral Vortex Keratopathy in a Patient Receiving Long-Term Ribociclib Therapy. (PubMed, Eye Contact Lens) - Sep 30, 2026 - "The patient had no history of tamoxifen, amiodarone, or chloroquine use, and there were no clinical features suggestive of Fabry disease. The patient remained asymptomatic, and systemic therapy was continued without modification. This case suggests that ribociclib-associated vortex keratopathy may be detected after prolonged exposure and remain clinically silent at presentation, highlighting the importance of careful clinical assessment to avoid unnecessary interruption of essential oncologic treatment."
Journal • Age-related Macular Degeneration • Breast Cancer • Cataract • Dry Age-related Macular Degeneration • Fabry Disease • Genetic Disorders • Macular Degeneration • Oncology • Ophthalmology • Retinal Disorders • Solid Tumor
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Ahmet Guzel; Ali Devebacak
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