INFECTION BURDEN IN MYELOFIBROSIS ON RUXOLITINIB: THE IMPACT OF TRANSFUSIONS, IRON OVERLOAD AND INFLAMMATION (SIE 2026) - Oct 6, 2026 - Abstract #C071; Pres time: Sep 22, 2026; 03:40 PM - 05:10 PM; Location: HALL 3; "Infectious risk on RUX was driven by prior in- fections, inflammatory burden, and transfusion related IO, while early spleen response was protective. Elevated NLR and IO emerged as simple, independent markers of infec- tious vulnerability, potentially guiding therapeutic choices and targeted prophylaxis."
Hematological Disorders • Herpes Zoster • Infectious Disease • Inflammation • Myelofibrosis
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F. Salvatore1,2; F. Branzanti2; M. Breccia3; M. Bonifacio4; E. M. Elli5; E. Abruzzese6; M. Tiribelli7; E. Morsia8; M. Farina9; G. Benevolo10; E. Beggiato11; N. Pugliese12; A. Tieghi13; E. Scalzulli3; G. Binotto14; F. Cavazzini15; A. Iurlo16; M. Crugnola17; A. Duminuco18; O. Mulas19; A. Dedola1,2; D. Cavallina1,2; N. Severi1,2; D. Cattaneo16; F. Cavalca5; M. Trawisnka6; B. Martino20; D. Cilloni21; C. Fava22; M. Bocchia23; C. Bosi24; F. Pane12; G. A. Palumbo25; G. Caocci19; C. Sartor1; F. Palandri1
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