A Multi-Omic Phenobank Reveals Axes of Glioblastoma Growth, Invasion, and Therapeutic Vulnerability. (PubMed, Neuro Oncol) - Oct 14, 2026 - "The HGCC Phenobank provides the first openly available PDX resource that systematically links GBM invasion phenotypes to multi-omic programs and therapeutic predictions. This framework enables reproducible model selection, mechanistic dissection of invasion modes, and phenotype-guided therapeutic discovery."
Journal • Brain Cancer • Glioblastoma • Oncology • Solid Tumor • ASCL1 • OLIG2
|
|
Anders Sundström; Cecilia Krona; Emil Rosén; Filippa Kruse; Hitesh Bhagavanbhai Mangukiya; Ida Larsson; Irem Uppman; Joachim Weischenfeldt; Johan Wikström; Karl Holmberg Olausson; Katrin Rut-Halldorsdottir; Ludmila Elfineh; Madeleine Skeppås; Maria Escriva Conde; Maria Pernemalm; Mats Nilsson; Maya Jeje Schuan Lü; Milena Doroszko; Ramy Elgendy; Rashmi Ramachandra; Soumi Kundu; Sven Nelander; Xiaofang Cao; Zankruti Dave
|