Leqvio (inclisiran) - Novartis
Nexletol (bempedoic acid) - Esperion Therap, CSL Behring
ezetimibe - Generic mfg.
Safety and tolerability of nonstatin LDL-cholesterol-lowering therapies: A systematic review and pairwise meta-analysis of randomized controlled trials. (PubMed, J Clin Lipidol) - Oct 8, 2026 - "Nonstatin LDL-cholesterol-lowering therapies were not associated with excess total or serious adverse events or consistent muscle, hepatic, or neurocognitive safety signals. Modest excesses were confined to tolerability-related outcomes (discontinuation because of adverse events and investigator-attributed drug-related adverse events) rather than major toxicity." 
Clinical • Journal • Retrospective data • Dyslipidemia • Familial Hypercholesterolemia • Genetic Disorders • Metabolic Disorders • Musculoskeletal Pain • Pain
http://www.ncbi.nlm.nih.gov/pubmed/42844101
 
Alessandro Aiello; Andrea Matteucci; Federico Nardi; Furio Colivicchi; Michela Bonanni; Silvio Fedele; Stefania Angela Di Fusco; Stefano Aquilani
 
Oct 8, 2026
 
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