Validation of Monte Carlo-Based Voxel-Wise Dosimetry in the Updated MIM SurePlan™ MRT: Application to 177 Lu Radionuclide Therapy (EANM 2026) - Sep 29, 2026 - Abstract #EP-1256; "Here, numerical consistency between these algorithms was assessed to determine the reliability of MC-based voxel dosimetry for 177Lu-DOTATATE therapy... Absorbed doses estimated using the MC-based MIM SurePlanTM MRT engine were consistent with the VSV method without substantial systematic differences in clinical evaluation. The constant increase in tumor absorbed dose with MC suggested improved preservation of spatial heterogeneity, whereas differences in low-density tissues emphasized the impact of transport modeling, suggesting that MC-based dosimetry might provide a more physically realistic representation in such regions. These findings support the clinical reliability of MC-based voxel dosimetry for TRT and suggest that MC-based dosimetry might improve dose evaluation in heterogeneous lesions."
Lung Cancer
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K. Miwa 1; K. Wachi 1; A. Komatsu 1; N. Miyaji 1; T. Yamao 1; N. Akiya 1; T. Horikawa 1; Y. Ogane 1; D. Mirando 2; M. Morimoto 3; A. Oishi 3; Y. Yamamoto 4; Y. Nishiyama 4
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